Scientists create gel to regrow tooth enamel in lab
Researchers at the University of Nottingham developed a gel that can regrow damaged tooth enamel in laboratory tests.
The new material mimics biological processes from early childhood to repair weakened enamel while reinforcing healthy areas effectively. It uses proteins that guide mineral formation instead of relying on traditional fluoride treatments for dental care.
Once applied, the gel creates a durable coating that penetrates tooth surfaces to fill microscopic cracks and gaps within the structure. This process attracts calcium and phosphate ions to form structured crystals that align neatly with existing surfaces.
Tests showed the regenerated enamel displays mechanical properties comparable to healthy natural enamel after exposure to brushing and acidic foods. The material restores both microscopic architecture and physical properties essential for protecting teeth against daily wear and tear.
The gel can also encourage mineral layer formation over exposed dentin to reduce sensitivity caused by receding gums or worn enamel. This approach aims to overcome limitations of existing treatments that fail to rebuild lost tooth structure completely.
“We have started this process with our start-up company Mintech-Bio and hope to have a first product out by next year”